Of 1,090 patients who underwent sampling 6-10 days after detection of a urinary LH surge (corresponding to cycle days 20-24), multiple logistic regression analysis revealed that endometriosis was positively correlated and male factor infertility was negatively correlated with absent β3 integrin subunit expression.
The subsequent probability of changing patient management altered ranged from 22% to 39% depending on the clinical setting.
Result(s): In 1,501 endometrial specimens, phase assignment-based integrin staining was 95% and 85% concordant with histology for the proliferative and early secretory phase, respectively, but only 54% and 49% concordant for the middle and late secretory phase, respectively.
The greatest disagreement occurred during the midluteal phase.
The presence of a hormone abnormality or of an inhibitor preventing hormone action could not be substantiated. [Show full abstract]Data provided are for informational purposes only.
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